Editorial methodology

Every claim on this site is tier-tagged and sourced. Here's how the sausage is made.

Who we are

We are an editorial team owned by Allermi, producing reference content on nasal sprays for allergic and non-allergic rhinitis. Drafting is currently AI-assisted, working from primary-source literature: FDA DailyMed labels, PubMed, AAAAI / ACAAI practice parameters, MotherToBaby (OTIS), LactMed, and StatPearls. The site does not currently claim individual bylines from named licensed clinicians. Bylines are role-based ("Editorial Team — Adult Allergy & Immunology", etc.). The published guideline authors cited inline (Dykewicz et al., Seidman et al., Carr et al., Vaidyanathan et al.) are the binding authority for medical claims, not any individual reviewer's personal credentials.

Evidence tiers

Every claim on this site renders with an evidence-tier pill. The scale, color-coded in the DOM, is the central moat of this publication.

Pill Meaning Example source
Meta-analysis Systematic review or meta-analysis (strongest)Cochrane review; Seidman 2015
RCT Randomized controlled trialVaidyanathan 2010; Carr 2012
Guideline Specialty-society practice parameterDykewicz 2020 (JACI); AAAAI
FDA Label Regulatory truthDailyMed Structured Product Labels
Cohort Observational cohort, case series, registryNBDPS; MotherToBaby
Expert Expert opinion / editorial (weakest)Editorial; physician interview

How we choose products

  1. FDA-approved (as an individual drug; compounded products use FDA-approved actives).
  2. Marketed in the United States: OTC, telehealth Rx, or in-pharmacy Rx.
  3. Used for rhinitis indications (allergic or non-allergic).

We do not review sprays used for migraine, smoking cessation, hormone therapy, or non-rhinitis indications on this site.

How we score products

Each product is scored 0–5 across:

  • Clinical efficacy: strength of RCT, meta-analysis, and guideline evidence.
  • Symptom coverage: sneezing, itching, runny nose, congestion, drip, eyes.
  • Onset speed: verified against FDA label + PK data.
  • Safety profile: common + rare effects; pregnancy, lactation, pediatric data.
  • Access & cost: OTC vs Rx, insurance, out-of-pocket.
  • Ease of use: frequency, tolerability, scent, alcohol.

Sources we use (tier 1: primary)

  • FDA DailyMed: structured product labels
  • PubMed: RCTs, meta-analyses
  • AAAAI / ACAAI: specialty guidelines
  • Dykewicz 2020 Rhinitis Practice Parameter: current standard-of-care
  • StatPearls (NIH Bookshelf): peer-reviewed drug monographs
  • MotherToBaby (OTIS): pregnancy / lactation
  • FDA.gov: regulatory statements, approval announcements, compounding regulations

What we don't rely on: manufacturer marketing, consumer-review aggregators without clinical verification, social-media anecdotes, and secondary news articles (we go to the underlying citation).

Quarterly refresh

Every MDX page carries a lastReviewed date rendered in the DOM. We refresh every page on a quarterly rolling cadence, re-checking FDA labels, new PubMed literature, guideline updates, and safety signals. Pages with material edits get a new lastReviewed stamp and a publishHistory entry. Pages reviewed + found current get the stamp refresh.

Affiliate and monetization disclosure

We do not run affiliate links, product-shelf CTAs, or sponsored content on any review or comparison page. The right rail is citation tooling (cite this page, mini-TOC, evidence summary), not a buy box.

Conflicts of interest

  • No pharmaceutical company advertising or sponsored content.
  • Reviewer payments are flat per article; never linked to any manufacturer outcome.
  • Editorial independence: pharmacist lead and medical reviewers have final sign-off.

What we don't do

  • Give personalized medical advice.
  • Replace your own doctor / pharmacist / OB/GYN.
  • Review products not FDA-approved or not marketed in the US.
  • Review homeopathic or unregulated alternatives without a clinical evidence base.

Summary & Recommendations

  1. Every claim carries a visible evidence-tier pill and a stable anchor ID for fragment citation.
  2. Primary-source-first: FDA DailyMed, PubMed, AAAAI/ACAAI, MotherToBaby, StatPearls.
  3. Quarterly review cadence with DOM-visible lastReviewed and firstPublished stamps.
  4. No affiliate revenue, no sponsored content, no pharma advertising.
  5. Every page serves as HTML, Markdown (.md), and JSON (.json), LLM-native from the ground up.
  6. Public claims library exposes every factual claim with its tier + source URL.

Publish history

  • Quarterly refresh; tier taxonomy verified.
  • Initial publication.

References

Databases

  1. FDA DailyMed: Structured Product Labels · NIH https://dailymed.nlm.nih.gov/
  2. PubMed · NIH https://pubmed.ncbi.nlm.nih.gov/

Societies & guidelines

  1. AAAAI · AAAAI https://www.aaaai.org/
  2. ACAAI · ACAAI https://acaai.org/
  3. Dykewicz 2020: Rhinitis practice parameter · JACI (2020) https://pubmed.ncbi.nlm.nih.gov/32707227/

Pregnancy / lactation

  1. MotherToBaby (OTIS) fact sheets · OTIS https://mothertobaby.org/fact-sheets/

Regulatory

  1. FDA: Compounding and FDA Questions and Answers · FDA https://www.fda.gov/drugs/human-drug-compounding/compounding-and-fda-questions-and-answers